We significantly revised our preprint on the modular biosynthesis of plant heteromannans and uploaded the new version to bioRxiv. Full-text: https://www.biorxiv.org/content/10.1101/2021.04.20.440611v2.full
Despite rising interest in the engineering of polysaccharide-based biomaterials, relatively little is known about how plant hemicelluloses can be built and tailored in non-plant cell factories. Pichia pastoris is a promising host to study cellulose synthase-like A (CSLA; heteromannan synthases) and CSLC (xyloglucan synthase) activities but the functions of specific protein motifs and the impact… Continue reading New preprint on yeast bioengineering to produce modular plant hemicellulose
We are happy to welcome Sooyun Lee and Tilman Jacob to the Designer Glycans lab. Sooyun first joined us for an internship in February to evaluate fluorescent reporters in Pichia pastoris. She will now start her MSc research thesis on secreting proteins from yeast to modify extracellular glycans. Tilman is a first-year MSc student at… Continue reading Two new MSc students join the lab
Debora Gasperini, Katharina Bürstenbinder and Catalin Voiniciuc are co-organizing the Leibniz Plant Biochemistry Symposium 2021. This annual conference will be focused on Plant Cell Walls this year, and will be held as an online event for the first time. We have an exciting speaker line-up and there will be free registration for participants from around… Continue reading Register now for the Leibniz Symposium on Plant Cell Walls
We are happy to have contributed to a new publication that appeared in Science Advances on the February 10. This study unveils how jasmonate signaling is initiated in the korrigan1 (kor1) cellulose-deficient mutant, and multiple ways in which it can be complemented. The work was lead by Stefan Mielke in Debora Gasperini\’s research group at IPB… Continue reading February publication update
By evaluating different mutant combinations, we discovered that brassica seeds with fewer heteromannan branches are more resistant to salt stress.
Wheat is one of the most important cereal crops on the planet. Here, we investigated the wheat enzymes are responsible for synthesizing mannan, a dietary fiber.
The first preprint of the Designer Glycans lab has been posted on bioRxiv, an open access repository for biological sciences
We published a review article in Plants (https://doi.org/10.3390/plants8110516), part of a special issue on \”Plant Cell Wall Biology\”. In close collaboration with multiple colleagues from Düsseldorf, we assessed the suitability of more than ten orthogonal hosts for synthetic biology and to study plant cell wall biosynthesis. In particular, we focused on the key advantages and… Continue reading Review of orthogonal hosts to study cell wall synthesis